Tube People and Making a Tube Person Setting?

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I've always been into the idea of a game where character creation is actually part of the universe. The people you're playing as were literally made somewhere; their skills, abilities, and talents all programmed into them, and once they were done cooking these humans were spat out to complete their tasks to whatever force created them. I know there are some settings that have tube people already (Paranoia) for one, but I think it'd be cool to have a game where mass production of humans is a major theme. Some good old fashioned "who am I?" philosophical sci-fi shenanigans.

Are there any games with this as a focus?
If you were to run such a game, what type of force would be creating these tube people? Corporations? Super governments? Aliens? Mad scientists?