Biopunk/Biotech/Gengineering Art

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Look up gigerverse/mundis carnis, prophet, and Splicers

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big fan of wearable biotech honestly

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>>54670015
>prophet
good fucking shit, I own all 5 volumes.

Splicers I found out about only recently, and I've seen the gigerverse stuff

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>tfw no dragon dog

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You guys ever read Ribofunk?

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gonna dump for maybe another half hour before I head off to sleep

>>54670096
I've been meaning to
What I have read is Seed by Rob Ziegler. It's pretty ok, most negative reviews complain about how dark the world is but I see that as a plus

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the Leviathan trilogy is also good

I'm really surprised no-one has posted those fuckable vehicles yet

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>>54670706
ikr? its great lets keep it that way

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im off to sleep now, if the thread is still up in the morning i'll find more shit to dump
regardless, I hope this is of use to someone

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>>54669974
Most biopunk ideas are lame and just normal gear and spaceships BUT MADE OF LIVING THINGS!
I prefer the approach that things like Resident Evil take in which they use viruses and other kinds of pathogens in bio-terrorism to create Bio Organic Weapons.

>>54670706
any vehicle's fuckable if you're brave enough

>>54672842
>I prefer the approach that things like Resident Evil take in which they use viruses and other kinds of pathogens in bio-terrorism to create Bio Organic Weapons.
Which is a pretty retarded approach. Why would you engineer a pathogen that engineers other bio-weapons if you could just engineer a killer pathogen and use that as a weapon?

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>>54670706

>>54673579
I must question the aerodynamics and power to weight ratio of this organism

>>54670184
How does this thing stand up straight

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>>54673605
Space magic

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>>54673737
>that thing
>space magic

>>54670666
>Can withstand the water pressure of the deep sea
>Adapt to the vacuum of space.
>Pressure
>Vacuum

Wat?

>>54673809
You may not like it, but this is what peak performance looks like.

>>54669989
Its always sad to see somebody with genuine talent try to make something novel which ends up looking derivative.

>>54670148
>Bee colonies.

Pardon?

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Sup

>>54673987
JAPAN
APAN
PAN
AN
N

>>54673987

Its simple.

Make an arthropod carapace and fill the joints with Sphincter muscles. Now you have an armor capable of resisting high pressures but hermetic for space walks.

>>54673987
https://www.youtube.com/watch?v=O4RLOo6bchU

>>54674072
IIRC as the whale floats along the bees collect nectar from flowers along the ground and use it to make honey which is at least partially metabolized by the whale in flight

>>54672842
Realistically, retroviruses are likely to be used in the process of modifying DNA, so the Resident Evil approach is at least somewhat viable

>>54670739
Okay fine, I'll watch Gargantia

>>54672842
Then you'll love what Google is doing in California right now.
>https://www.theverge.com/2017/7/14/15972950/mosquitoes-google-alphabet-verily-debug-wolbachia-bacteria-fresno-california

>>54670276
If you don't take your gun to the shooting range twice a day, it will become lethargic and could develop behavioral problems.

>>54675492
Geneticst here. No. Thats not how anything works. Retroviruses are a tool for DNA modification, but they are far to limited in scope and precision to be useful for anything you need to work consistently.

Shame, I would contribute but all the bio-armor related images I have are smut.

>>54676143

Can't you just say that you just added more proteins on the capsid and enzymes to give it more autonomy and ability?(like linking complementary DNA strands to enzymes to precisely locate the parts of the chain you want to modify)

So you Have different responses for different tissues with a huge viral load for every different tissue or having a multipartite(I don't know how its said in English; they are viruses that enclose different part of the DNA in multiple capsids, mainly seen in plant viruses) formed in statistical proportions of different viruses specialized.

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>>54676207
Surely some of them are SFW?

>>54676232
The thing you're missing is the degree of complexity that entails. We understand bio-molecules as small, which makes us think they are simple, or somehow elemental albeit massively diverse and idiosyncratic in their action. In reality, they are very unstable, and only serve their function by attrition. Its not uncommon for a process to throw a million copies of something at a problem to have it solved correctly a handful of times. Viruses work because they use as few parts as possible; there are only two points of failure. Each element you add adds several more points of failure, both in its active site, and whatever site keeps it bound to the complex as a whole. Thats to say nothing of dimerization of disparate elements.

This creates a common pitfall for people who are learned but unpracticed in molecular biology: it is very easy to come up with complex, well thought out structures that achieve complex and important goals. However, in reality, the capricious nature of bio-molecules is not so well understood, and all it takes is one unintended action or interaction to cause the whole system to fail. Even our most advanced antibody therapies use three or fewer components for this reason.

>>54676232
Even if you could, you're missing the point of a biological weapon, which ultimately is to kill the enemy as efficiently as possible. A better use of the technology would be something like FOXDIE.

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>>54670184
i like this guy's art

it's all very bizarre

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>>54670514
The rest of Keith Thompson's Borderlands work.

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>>54676616
>6

>>54676616
>>54676628
its a shame that Kieth's only work nowadays is on the shitshow that is Warframe.

>>54676840

I didn't know Keith Thompson was still working on Warframe? In fact, I thought he only did some early designs?

>>54673575
The point of the T-Virus wasn't to engineer bio-weapons, that was a side effect. It was originally intended to evolve humanity into a "god-like" and/or "immortal" state by inducing a specific sequence of rapid mutations.

>>54676882
Even the newer stuff reeks of a poor interpretation of his hand. I assumed he was still on with the project for a more consistent income stream.

>>54676610
>doritohead

>>54676840
These days I think most people see Warframe as just a collection of neat artwork with a poorly designed game hanging off it like a dead conjoined fetus, so in a way it's not that different from if he was just working on his own universe which wasn't attached to anything. It's not a waste if it's the only part that anyone remembers.

>>54676610
The idea is interesting but its not clearly thought out. It would be interesting if everything that would normally be a mechanical component was a human-analog organic component (which he does already) with the right use-case (which he doesnt). Its all just vaguely grotesque, which is neat but not necessarily evocative.

>>54669989
>>54670126
>>54670352
>>54670446
>>54670493
>>54670367
>>54670276

I did not know this genre existed. God it is cool!

>>54677090
Id say that the realization of his style has been poor. Everything is far too chunky compared to his sleek, composite organic designs. Nearly every design feels like a balloon animal, especially the standard enemies. Ultimately the game's failing is tone and implementation. Just sitting here on my couch I could think of a dozen changes to Warframe that would each make it worth playing, but as is the designers seem more focused on making a 3D version of Gaia online.

>>54670739
So fucking mad this series isn't getting continued.

>>54677264
It kinda blew its load in the first season.

>>54677090
No people are just addicted to the grind to be able to play the little amount of good game play and story there is.

>>54676425
Hmm... I get what you say, but to some extent I would argue that the part where we know how to fold proteins, make them self assemble into the quaternary level as we want and have very little variation for stability is akin to people saying that they use Inertial confinement fusion reactors or Artificial General intelligences on pentiumIVs in their stories.

We are not going to delve much into the details and to satisfy the hard-science autism sense we just need to throw numbers and mechanism that at least explain how the system works, and it should be done in a comprehensible level.

For example, I can just say; I use a highly modified Brocadia anammoxidans to get hydrazine and use it for maneuver propellant in my ship or gas in my rifle, and if someone start asking questions say that instead of taking 1 week for every generation you put it the generation number under 1 minute and accelerated the general metabolism with increased avaliability of nutrients while giving a regulatory process in which the accumulated hydrazine in the anammoxosome is released when it reaches a certain trigger(maybe the bacteria enters the stationary phase, maybe when a certain volume or molarity inside, as far as I know triggers in biological organisms aren't rocket science).

So, it wouldn't work in real life? No, but it now has a plausible basis and adds credibility and richness to the universe, which is what we are looking for in the end.

>>54677308
>we know how to fold proteins and make them self assemble into the quaternary level as we want.
No. We dont. We know how naturally occurring structures do so, and we copy those domains. Even then, not all complexes operate properly.

I do this for a living, Im not just some pop-sci enthusiast.

I see your point though that using something thats at least semi-plausible does lend some credibility to a narrative, but at the same time most people dont really care either way. A virus is a virus to the layman, and as long as you tell people what it does, they wont care how.

>>54677283
It's a pity, the juxtaposition of the space war and the people living ordinary lives in floating cities was what attracted me to it. But I think a lot of people preferred one or the other and the producers weren't able to maintain the balancing act.

>>54677364
Yeah. It didnt know if it wanted to be aqua-k-on or Gundam V Squiddam. The two are fairly mutually exclusive in tone and scope. The show would have been much better if it were told from the native's perspective entirely rather than starting us off with space stuff.

>>54677358

I intended to say that we don't, I don't know why I left out the "not" in that phrase(If we knew Earth would probably be much more amazing)

Most people don't, care, but from my point of view a story needs to have some real life anchor to it so it doesn't stray into the magic unicorns and we can call it realistic.

To have that anchor, we need detailed descriptions and the deeper they go the more consistency is added.

In the end, yes it's a matter of preference.

>>54676207
post them anyway

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OP here, will resume dump now

>>54676425
this is very interesting
would you say that gene-drives might smooth out bio-molecule interactions?

No battle angel Alita?

>>54677664
Gene drive tech is irrelevant to the structure of product proteins/complexes/etc. Gene drives are just complexes which force inheritance.

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I was digging around the archives earlier and found this
i need to look at it more in depth but its a pretty cool setting from what ive seen so far
download:
http://www.mediafire.com/view/mqz3nfzitnpmxeu/Core's%20Crusade%20-%20Mechanical%20Aspect.pdf
http://www.mediafire.com/file/hae42fd2x42da8s/Core%27s+Crusade+-+Dream+Aspect.pdf

>>54677709
yeah that makes sense, thanks for answering bud. i'm majoring in bioengineering so this shit interests me

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this shit is weird http://daemoria.deviantart.com/art/Posthuman-606140673

>>54677778
Be sure to pick up some experience in High Pressure Liquid Chromatography (HPLC), its in really high demand and I regret not learning it in my undergrad.

Got any other questions?

>>54676425
Might a solution then be to use a more complex organism like a fungus or worm to get around the stability problems? I'll admit that this is way outside my area, but my understanding is that error correction is a prerequisite for multicellular life.

>>54677264
>>54677364
Did you watch the OVA? It ends on a fairly interesting sequel hook, though if it does get continued it most probably would be centered around a completely different cast.

>>54677264
I think I'd like it more if I didn't see it so often on /pol/.

>>54677961
Yes, but then you end up with a system that is much larger and therefore much more susceptible to detection and response (the strength of viruses is that even to cells they are like toxic dust motes), and that a more complex organism has more complex metabolic priorities such as specific nutrients or reproductive strategies, meaning that it may settle into a more productive "behavior" that is more beneficial to itself but less productive for you and your goals.

Evolution is more varied than people realize; if such a thing were viable, it likely would have occurred at some scale. For example, there are demi-protists which contain cells within cells within cells nurturing and hosting multiple generations internally that then burst forth with the death of the parent-host, others which feature a fully formed linear digestive tract in a single cell, and others which have motor apparatuses that would put even the most speculative nanotech to shame. However, interesting as these solutions are, they have stayed small scale because they are not very efficient relative to the complexity they add.

>>54677967
I did. It still has scope problems.

>>54677364
>>54677402
I don't quite think it's trying to be either of those things. Gargantia, ultimately, is a clash of civilizations type show with a touch of fish out of water. The Squidam opening is necessary in order to show the kind of society Ledo comes from, and the Aqua parts are essentially all set up for Ledo's eventual character arc post episode 9. It's not trying to be either of those things, but it's own story where both those segments serve as key components.

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Anyone else read this?

>>54678083
Why would it not be more interesting to start with the easy to understand boat-folks, then slowly reveal the massive space bullshit going on in Ledo's life throughout the season as he opens up and responds to new things on earth? As is, the show introduces itself as one thing, becomes another, and constantly flirts with breaking its own tone to return to the scale of its opening.

>>54677961

I was about to say that to solve what he says, you simply add metabolism to keep the added complexity in check and scale the whole thing to increase the number of mechanisms.

The problem is that then you need a barrier to keep that metabolism and regulation in check, and also you need a way to regulate that barrier to have your own controlled microcosmos to play with...

And the more things you want to do, the more you realize you are creating eukariote cells, and when you want them to do more awesome shit you start to coordinate those cells... and by the time you end you probably have somekind of synthetic pluricelular parasite that looks like a Platyhelminthe

And that kinda defeats the purpose in the first place. Since the momment you added metabolism you stopped having a virus and started having some celless protein-only bacteria that wouldn't have lasted much anyway(although DNA altering Platyhelminthes parasites do seem interesting)

>>54678132
Yeah, this actually reveals something important about biotech: at a certain point you're just better off having a person do it. It will always be cheaper to have a war then make a perfectly engineered mind-control hyperplague.

>>54678040

I would say that evolution has tried many things, but it has done so under constant constraints and with the resources it had avaliable. We will never seen Lithium or Tungstem optimized enzymes because they weren't that available for living things to test constantly through years and years, and no one knows what kind of weird mechanisms appear when you start using chemistries could never use or implement.

But, on the other hand, when we start directing things in our bodies things might change. If your baby don't have to dedicate energy to form a reproductive system you might get it out much earlier, and require less energy when its an adult, or even better substitute your reproductive organ with an expanded digestive system much efficient.

For reproduction just take your stemcells and put them in a medium that promotes their differentiation into sperm or ova.

And even better, if your are not retrained by nutrients(just see how many fat people are around) you can maintain more complex and bigger systems, adding muscles and muscle mass and fiber types shouldn't be a problem but rather an advantage in our world.

Although I would say that much of this falls under pure imagination, since we don't even know how to start doing any of this, and even if we were it would be some gigantic singularity AI simulating entire quantum universes within itself the one who would design the biochemical pathways and building blocks required... still I think I'm at least right on the fundamental theoretical level, which is what we need to create a biopunk world anyway.

>>54678128
Because, ultimately, it's about Ledo and his journey. Apart from being the viewpoint character, keeping the audience in the dark about where he comes from and his circumstances would just make his subsequent actions inexplicable until he explains them and create a disconnect between the audience and Ledo.

Considering that the series is entirely about Ledo's journey, a disconnect between the audience and Ledo is potentially fatal to the story as a whole. Even if it doesn't, it would still lesson the emotional impact when the big reveal happens and he figures out the truth.

I mean, it's not that it couldn't be done, but doing so will require a massive change to the structure of the show itself, possibly to the point where it might as well be a completely different show.

>>54678360
I just dont see why it needs to be Ledo's story. He's not terribly interesting, especially when we know everything about his motivations from the get-go. I just think it would be more interesting for the show to start from the ground level and work its way up. Thats how TTGL manages to do fucking galaxy-chucking shenanigans but still make us give a shit about the little things.

>>54678335
Increased muscle mass is actually something we can do already in lab animals.
https://en.wikipedia.org/wiki/Myostatin

>>54678335
The reason we see the chemistry we do is because it works well. There is far more silicon on earth than carbon, but it bonds much less strongly. It may be possible for life to arise from non-carbon chemistry, but it would be far less stable and therefore take much longer to accumulate and flourish.

>>54678434
Yes, but it depletes the stemcell beds.

>>54678434

Yeah, I also remember some anon in /sci/ saying that his team found that only one gene was regulating muscle growth but the whole thing was shut down by the government .

I don't remember the whole thing, since I saw it in a greetext that I didn't save and it probably holds as much truth as any other greentext story you see here(none) but still was an interesting read.

>>54678473

Yes, but maybe its because it lacked the required energy. Silicon lifeforms might form if the surface temperature is around 400-500Cº(If I remember correctly)(And I would say that it would work by increasing the activation energy of reactions that wouldn't have happened on our conditions and allowing silicon to form bonds more easily) and if the general pressure is way higher, water might still be a liquid, but on this temperature range other solvents might be more optimal or simply allowed.

>>54678607
You're going to need some heavy-duty lab equipment to run biology experiments at 500 degrees.

>>54678424
TTGL is a story where a lone village grows to be come a planetary, then a galactic superpower. Gargantia is a story about a soldier from a military fascist state gets tossed into a society with completely different values and culture, and how he deals with that and the ghosts of his past. Switching the viewpoint away from Ledo would mean completely changing the themes and the story, to the point where you might as well be writing a completely different story.

Ultimately that's not the kind of story Gargantia is.

>>54678607
You're right that there are niche environments where non-carbon chemistry becomes efficient, but the energy of such an environment only further hampers stability. Carbon is present in life not only because it is stable, but because it is flexible. Complex small-molecule carbon compounds are still stable at high and low temps.

>>54678682
I still disagree that Ledo's perspective is necessary, mostly because he himself does little to explore his ghosts, while the other characters do most of the reacting to the revelations he brings. I agree that changing the story would change the story, but I still argue that it would be better. Regardless of the trajectory of TTGL, it manages the juxtaposition of its two worlds, whereas Gargantia never really does.

>>54678646

Which makes me remember that to this day, many deep microbial species haven't been adequately investigated for this very reason. The equipment is too expensive and the conditions have to be constant and perfect.

The last one I read about was Pyrococcus furiosus when I wanted to investigate about single chamber biofuel cells and didn't know that required platinum as a catalyst, which is expensive as fuck(but at least it was a battery that could work at around 100ºC, or better said; requires 100ºC to work, otherwise it dies)

>>54678684

>Complex small-molecule carbon compounds are still stable at high and low temps.

Yes, but as far as we know that goes from -50Cº to 150ºC which is a huge margin but the carbon atom is cheating, it had millions of years to form complex compensation mechanisms to keep itself together, as a system, in such ranges.

A silicon lifeform that works under the 400-500Cº should also expand its capability temperature once it tries to reach new colder-warmer places that haven't been filled before by simple trial and error.

>>54678761
Im not talking about organisms, Im talking about chemistry. Carbon chemistry is stable well outside that range, pressure allowing.

>>54678727
What juxtaposition? TTGL never does much juxtaposition, mainly because it never explores it's two worlds to any significant degree. The closest it's come is the horizon scene at the end of the first episode.

Gargantia on the other hand is entirely about the juxtapostion. It's core to it's central story as a fish out of water story, right up to the point where Ledo makes his decision at the end to discard everything that he has grown up under to side with the people of Gargantia.

Frankly, I just don't think you understand what Gargantia is about. All the space gundam and Aqua stuff is eventual setup for the clash of worldviews that form it's climatic arc.

>>54678912
Is there a manga or something?

>>54678682
They could still do a fish out of water story by switching the viewpoint to a Hideauze in unusual circumstances.

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oops I had to leave home for a bit
gonna post splicers art for a bit

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I'm all out of splicers
gonna post a few more images and call it a day, good thread lads

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And with this vaguely related image I'm tapping out
siesta time

To the geneticist(s), Anon, if he is still in this thread:
What do you think will be the next breakthrough into bio-engineering? And what do you think will be the first wide spread form of genetic engineering?

>>54681832
is that a knife through her head?

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post transhumans

>>54684283
I dont think so but its deviantart so anything is possible

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>>54684818
I really really like Abara.

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>>54684847

>>54678021
The people on /pol/ don't understand it, just like the Zeon fanboys don't understand Gundam.

I mean, the author is dead and everything, but I think Gargantia is pretty clear that the whalesquids did nothing wrong, the federation's obsession with purity is bad, and the Gargantians have a better lifestyle, even if it's fragile.

>>54677967
Well, I think the only real way to make Gargantia work is as a franchise with more than one cast and narrative. Like others said, scope problems out the ass. I can see what they seem to be trying to do with the Juxtaposition of the space war and the slice of life bits, but people keep missing the forest for the trees, and the writers don't seem to know how to pull it off convincingly for everyone.

>>54677402
> It didnt know if it wanted to be aqua-k-on or Gundam V Squiddam. The two are fairly mutually exclusive in tone and scope.

That's the thing. The whole conceit of the show is that they really aren't. The fragile peace of Gargantua is Contrasted with the Space war, and the audience, like Leddo, is asked what they'd rather fight for. Any perceived tone shifts roughly coincide with the Protagonist's own feelings.

Can he stay on Gargantia, knowing that there is a war going on somewhere else, and that all this could easily be destroyed, or does he stay and enjoy all the cute things going on around him.

That's what I think the writers were trying to do. But judging by the sales and divided fan-base, that clearly didn't work. People were too quick to chose one side or another.

Anyone remember that set of images about particulate demons?
Not strictly related to the thread, but some similar themes.

>>54682806
On the road. I'll answer tomorrow. Long short: computational prediction of sequences associated with binding domains.

>>54685069
Personally I didn't give one shit about the space stuff, but that's mostly because the scale and stakes of it are poorly defined.

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>>54686613

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>>54686631

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>>54686654

>>54686613
>>54686631
These.. are really fucking cool, I wish i had that much time on my hands.

>>54684986
>Zeon fanboys don't understand Gundam

Why don't you say that to my face, Feddie bastard?

SEIG ZEON

>>54693728
>Insulted
>Interrogated

Those are some mean tentacles

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>>54693952
>VE VILL ASK ZE QUESTIONZ HERE

>>54684389
I would post the mandatory All Tomorrows but im not home
Its not like anyone hasnt seen it anyway

>>54693749
neat.

Where did all this new Splicers art come from? I've got the Core Book, but didn't know there'd been supplements added to the setting.

>>54693308
>Ultraman
>The God warrior from Nausicaa, and thus the Evangelion, and Anno's Godzilla, are all just Ulraman.

>>54698370
>just

>>54678111
Yeah, bretty gud.

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>>54699833
Yay! Someone noticed me!