Longevity research: what seems the most promising?

>>9132882
Why are there so many edgy effete dilettante misanthropic nihilists on /sci/ nowadays?
Leave, for goodness' sake.

>>9132871

>1) SENS
>*power gap*
>9000) metformin, rapamycin
>9001) parabiosis
>9002) telomerase
>9003) caloric restriction

>>9132890
That's more like it!
Thank you, anon.

https://ocw.mit.edu/courses/biology/7-342-the-biology-of-aging-age-related-diseases-and-interventions-fall-2011/

>>9132893
btw, SENS really is the most promising one: look up senescent cells clearance, it's an exploding topic in biotech right now (unity biotechnology and oisin biotechnology being the biggest name around) and it all started years ago from SENS, where Aubrey De Grey included senescent cells among the 7 types of damage to repair

6/7 to go now ;)

>>9132908
>>9132909
Thank you.
Sorry for the belated reply.

>>9132890
>caloric restriction
Works great if your body mass < 5 grams

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>>9132882
If you want to shorten your life so bad, you already know the best way.

>>9134236
That's why it's ranked 9003th

>>9134230
stop posting those fugly bleached koreans you bitsch

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>>9134230
>Refute
You can't refute opinion, only disagree.
Your subjective thoughts, aren't objective fact.
>Filename

>>9132882
>>9134230
>Korean acts like Westerner.
>Ruined, confirmed!
Well done, you've ruined yet another nation.

>>9134236
>Works great if your body mass < 5 grams
See
Colman, R. J., R. M. Anderson, et al. "Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys." Science 325 (2009): 201-4.

>>9132909
I'm extremely excited about this!

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what immortality do you want guys

dumping

>>9134450
>>9134452
All of them.

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this one is not really immortality

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nanomachines son

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>mind uploading
>you
>not a copy

nah

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...lol

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last one

this is the one that i really hope happens, this is the true meaning of transhumanism

These immortality paths pictures were all made by Maria Konovalenko, who is a longevity researcher and also a qt

>>9134396
Sorry if plebbit but you should really join us on r/longevity

Our goal is to spread the word and raise funds as much as we can, to get rid of aging asap

>>9134450
>>9134452
>>9134455
>>9134460
>>9134467
>>9134470
>>9134478
These are excellent, if /sci/ was more active and contained less of (>>9132882), I'd start a longevity/transhumanism general.

>>9134552
I'll give it a look, thank you.

>>9134521
Very qt.

>>9134599
What got deleted?

>>9136688
You can find deleted posts on https://warosu.org/sci/

>>9132871
Not using devices that generate pulsed microwave fields.

>>9134460
This just made me burst out laughing. The whole thing literally described cells. Programmable self replicating machinery, ie, cells.
>Nanomechanisms for targeted drug delivery and destroying tumors
You mean NK cells, antigens, and peroxynitrite / H2O2 generation. The basic framework for synthesizing and trafficking compounds, and identifying the programmed target. The only advantage synthetic nanomachines have is some theoretical ability to act as mere storage vessels for a magic "targeted compound", or the ability to destroy a target mechanically. Though this could likely be done better with the mechanisms that already exist.

>Diagnostics based on nano sensors
The body already does this.

>Microrobots thombrosis dialating blood vessels
Already signalling pathways to do this.

>living cells programmed to perform specific tasks in the body
...like the cells we already have?

>Nanomechanisms capable of performing functions of specific cells
Why? Are they really going to be able to outperform oxidative phosphorylation? Will they really have as efficient and fine tuned signalling mechanisms? ERK, ion channels, etc?

>integrating into a cell, repairing it, and controlling the genome
Like the cell already does. Cells already have error detection and repair machinery for various structures. You can't just magically detect and perform fine grained "fixing", and you can't magically get rid of free radicals better than superoxide dismutase, gluthionine reductase, etc. What's it going to do, just magically get rid of iNOS when it's gone awry? Just push Ca2+ or whatever out of the cell? How?

>synthesizing any organic structures
Like... normal cells?

>Replacing most cells with nanomechanisms
Cells already are nanomechanisms.

>Neurological expansion, networking, data externalization, interfaces, etc.
This is a valid point. Lot to be said about it.

Yes, I read all the old sci-fi, watched the movies, played Deus Ex,etc.Most of this is just "feels cool".

>>9136760
This is a very good post, as autistic as it may be.
Just wanted you to know, Anon. Please, keep posting.

>>9136734
Jesus christ not you again.

Elizabeth Parrish has more balls than anyone here.

>>9136951
https://www.bloomberg.com/news/videos/2017-08-24/bioviva-uses-genetic-therapies-to-fight-father-time-video

>>9136951
eh, most of the telomerase got washed down the toilet, she said delivery wasn't good enough to actually rejuvenate her