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PROCRASTINATION - DRUGS

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/Sci/


Do you think it is worth it to jump into any of the following meds to beat procrastination, as someone who is ruled by it despte meditating, exercising and eating healthy? It's a constant battle I seem to lose more often than not.


Possible meds include

>Dexamphetame (Or the mixed salt version, Adderal)
>Bupropion (Dopamine and Noradrenaline reuptake inhibitor)
>Selegiline (MAO-B inhibitor (only increases dopamine)


>Ones I've tried but didn't work well

>Methylphenidate (I cannot remember words on it and the come down makes me suicidal, the worst drug I have ever tried in my life)
>Modafinil (Sometimes it works, sometimes it doesn't. Sometimes it makes me feel so disconnected with the world, everything seems fake)
What's your opinion? I think I'll give Selegiline a try since it has a long half life, only seems to increase Dopamine and seems fairly well-tolerated long term with some talk about neuro-protection compared to the rest.
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>>8912829
Adderal only has an effect if you ADHD. If you don't have it, it's just placebo; Don't waste your money on that. Take some Nootropics, that'll help more than most.
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>>8912883

>Adderal only has an effect if you ADHD


You sincerely think Amphetamines don't have any effect on the healthy population, really?

--
I already take noots, Bacopa, Lion's Mane, Vitamin B, Zinc, mag, melatonin..I eat 6 eggs per day for the choline too. It's not working.
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>>8912883
>Adderal only has an effect if you ADHD.
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>>8912829
>Methylphenidate (I cannot remember words on it and the come down makes me suicidal, the worst drug I have ever tried in my life)
I can read just fine but yeah the come down is pretty bad.
Unfortunately adderall and vyvanse aren't sold where I live.
>>Modafinil (Sometimes it works, sometimes it doesn't. Sometimes it makes me feel so disconnected with the world, everything seems fake)
Didn't do anything for me.
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>>8912951

>Didn't do anything for me.

Modafinil is really strong for me, sometimes it works great but the most remarkable effect I have noticed while on it is something a bit hard to explain, and that's that every single object I see appears to be more grounded, looks heavier and more real, and I can really feel the form of the object by looking at it, as if I were seeing it in a 3D model program. Maybe it's the mere increase in attention giving me that, but damn I never get that no matter how much I meditate or take stimulants.
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Lisdexamphetamine.

It's dextroamphetamine (Adderal) but better and safer. The drug's release is slower so the effect is long-lasting and it has less potential for abuse.

It's also approved as treatment for binge eating disorder.

>>8912883
>Adderal only has an effect if you ADHD. If you don't have it, it's just placebo; Don't waste your money on that.

Med student here. I have ADHD and treat it with lisdexamphetamine. I've seen a lot of people take drugs to help with their studies. Some people have even tried to buy my prescriptions.

It works. People are a lot sharper when they're on stimulants. They learn better and faster and make less mistakes and participate more in activities. It's like night and day. These people essentially become hypomanic, which is a great trait to have when you want to "exceed expectations".
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>>8913028

>Lisdexamphetamine

Are you not worried about the long term damage Vyvanse might cause you?
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>>8913082
What are you referring to?
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>>8913124

De-regulation of dopamine receptors, life long reduction of hydroxilase and well, just plain dependence on the drug to enjoy anything in life, let alone do work.

Also, how do you deal with the up and downs?

>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328278/
>>
>>8913082
not him but
long-term effects of Vyvanse abuse include:
>Malnutrition
eh I survived on Ensure for a year once when I had a weird undiagnosed medical issue
>Stunted height and weight in children
I'm already stunted, 5ft tall
>Paranoia
hah too late for that one
>Hostility
too late
>Psychosis
so basically the same possible outcome from any mind-altering substance

idk senpai doesn't seem that bad, coming from an ex benzo user
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>>8913132

Do you not develop tolerance to the drug at some point, rendering it almost useless?
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>>8913128
That study applies to dextroamphetamine, which is the active drug. However, vyvanse has it bound to lysine, forming a prodrug. It is cleaved by a rate-limited enzyme in the blood, slowing down the release of the active metabolite.

According to my studies, dopamine release and drug addiction are connected to the speed at which the drug enters the brain. Vyvanse should be safer than Adderal in this regard.

I used to take it every day. I did that for about one year. I don't recall having any withdrawal symptoms when I stopped.

>Also, how do you deal with the up and downs?

Honestly, my entire life is about ups and downs, since forever. ADHD is like having a brain with a built-in bullshit detector I can't turn off. I have trouble even noticing the existence of boring stuff but when it comes to interesting stuff I have deep attention. It's as if my brain's signal-to-noise ratio is all fucked up; it needs an extremely strong signal in order to focus. Most of the time is down time for me, and then I'd somehow find one interesting thing to latch onto and it'd consume me for weeks.

I take the drug to help me cope with medical school bullshit so that I can focus on the stuff that really turns me on like neurology, psychiatry, radiology. Not shit like obstetrics. I couldn't care less about that.
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>>8913164

>According to my studies, dopamine release and drug addiction are connected to the speed at which the drug enters the brain. Vyvanse should be safer than Adderal in this regard.
Wouldn't Selegiline then, be an even safer option?


>I take the drug to help me cope with medical school bullshit

So you don't take it everyday, but rather, as needed? What about tolerance?
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>>8913132
Abuse being the keyword.

I took a full 70 mg dose today with no gradual escalation after a week of abstinence. I experienced strong anxiety, nausea, stomach pains, tachycardia (120 bpm) and hypertension (160 x 90 mmHg).

The reason I stopped taking it daily is I was trying to figure out my blood pressure. Amphetamines can raise basal blood pressure and raise cardiovascular risk so at this point I started worrying about my own health. I'm pretty sure it's connected to my high anxiety though. Whenever I'm anxious about something I measure it and it's 160 x 90 mmHg, even though I didn't take any stimulants. I consulted with some actual doctors and one cardiologist, they all measured it and it was 120 x 80 mmHg.

So now I take some beta blockers as well because God knows I can't step foot into medical school without my BP rising.

>>8913181
>Selegiline
>MAOI

Antidepressants can elevate the mood of depressed people but it probably won't help those without mood disorders.

Also, I have an extremely low opinion of MAOIs. I have never ever seen a doctor prescribe one. The absurdly big list of serious drug and even food interactions might have something to do with it. Don't think I will ever prescribe or use one, either.

>So you don't take it everyday, but rather, as needed?

I used to take it every day. Now I only take it before exams.

>What about tolerance?

I was pretty tolerant back then. I no longer experienced side effects and the drug's euphoria and grandiosity was gone, leaving behind only a deep concentration and drive. It was pretty amazing if you ask me.

Now every time I take one it feels like it's the first time. Makes me anxious and I want to learn fucking everything all at once to get it all over with and go the fuck home.
>>
Most medications are bad, the literal best way to end procrastination is to stop masturbating/looking at porn, and walk more in sunlight.
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>>8913258
Based /x/bro.
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>>8913258
I was diagnosed with ADHD in the middle of medical school. Before that, I used to cope by using my classmates.

Most of them would sit in some dark place and cram shit all day by themselves but I managed to find a small group of friendly people who actually cared enough to discuss the subjects. So I'd sit among them and start participating as well. I've always found that to be pretty engaging way to learn and retain knowledge. Way better than sitting around in a class listening to some faggot's unending lecture.
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>>8913255
>I have never ever seen a doctor prescribe one.
I think psychiatrists stopped using them when they possibly can because they have a nasty tendency of killing you if you have less than perfect self-control and discipline? Which is sort of an occupational hazard for the people who need them.
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>>8912883
I was under the impression that only applied to dexamphetamine. I recall reading that the other isomer in Adderall actually had a positive effect on concentration in people without adhd. I say that having used it without adhd (or at least without a formal diagnosis) whereas dexamphetamine (more specifically lysdexamphetamine, the prodrug, aka Vyvanse) made me feel like a tweaker and I had a hard time concentrating and reading people.

I also do not find methylphenidate to be helpful, except at making me abnormally angry for no particular reason.

The best use of modafinil and adrafinil is when you're sleep deprived. Their effects are most noticeable then. I'd use them after all nighters so that I could attend class.

I also took bupropion as prescribed but it did literally nothing but cause occasional mood swings. After 4 weeks it had zero impact on my behavior. In retrospect, it may have actually worsened my procrastination while I was on it.

Lastly, an mao inhibitor seems like a hassle because you have to be careful of what you eat. Never tried that though.

Another rather unknown substance that might help is prl-8-53. It improved my working memory. I was accidently remembering things like phone numbers and I managed to memorize a 40 digit number in a few minutes while I was waiting for something. You can do your own research on that.
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>>8913273
In general, MAOI impose severe restrictions on your diet and other treatments. They're pretty much the last line of treatment now. Everything else has to fail before you risk using one of these things.

If you eat anything that contains tyramine (cheese is a classic example) you get massive norepinephrine release and an hypertensive crisis. Selegiline targets MAO-B only, so at least it doesn't have this nasty interaction.

MAOIs interact with so many drugs it's not even funny. I frequently check psychoactive drugs for interactions and MAOIs would invariably be among the list.

Shit even makes nicotine more addictive somehow.
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>>8913360

>Selegiline targets MAO-B only, so at least it doesn't have this nasty interaction.


This is why I am interested in the drug. Seems to me any drug that increases dopamine, even slightly should lead to improvements in mood, concentration and drive. I'll be a hassle to get a prescription of Lisdexamphetamine, but Selegiline is easy and cheap to buy online. 30 bucks for half a year prescription is pretty good.
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>>8913376
It's only selective for MAO-B in lower doses and you're still risking all the other interactions. Do you really want to take a drug that can randomly interact with a random vitamin supplement pill you took without thinking?
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>>8913397

>Do you really want to take a drug that can randomly interact with a random vitamin supplement pill you took without thinking?

I am not sure what sort of interactions one will find at 5mg daily, it seems that as long I do not enter the MAO-A inhibition, it's a pretty doable medication. I also suspect having a smaller, but more sustained increase in dopamine is going to be more beneficial for me in the long run, not just for addiction concerns, but to mitigate negative thought patterns and impulses, increase general well-being and drive.


I've tried Vyvanse before, it felt pretty great being on it for the 12 hours it lasted, but the comedown made me feel so shitty, I didn't want to take meds anymore, let alone work on my projects. That constant change in drive really makes things meaningless to me. If it doesn't work, well at least it was just 30 bucks.
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>>8913348

>prl-8-53.

I also plan on giving this a try. Working memory is not my strong suit at all. Currently on the second week of Bacopa Monneri supplementation, I haven't noticed much improvements in memory yet, just a sedating effect.
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>>8913414
I didn't like the sedating effect so I stopped taking bacopa monnieri after a few days. I think the memory effects were suppose to max out after 2-3 months with that but it didn't seem worth it. Out of all the nootropics I tried, prl-8-53, phenylpiracetam, pramiracetam, and idra-21 (I think that was the name) had the most significant effects. Idra-21 was weird though. I've taken a lot of things in my time by the idra-21 was the strangest substance by far.

Prl-8-53 was definitely the most beneficial for daily use out of everything I tried. Adrafinil was the most useful for occasional use, specifically for sleep deprivation. Most nootropics (specifically the racetams) don't do much for a young healthy person from what I researched.
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>>8913432

I'll definitely get ahold of some PRL-8-53 next, alongside an order of Selegiline from India. Could you explain how Idra-21 affected you?
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Where do you buy this shit?
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>>8913445

What shit?
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>>8913449
All this shit.
>>8912829
>>8913028
>>8913348
>>8913360
>>8913432
I want 2 be to intelligent to.
>>
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>>8913456

1. Go to r/Nootropics and start learning
2. Go to your doc and make him give you a diagnosis for ADHD
3. Get cryptocurrency and buy meds from the black market
4. Buy meds from online Indian pharmacies
5. Suffer from Depression and obsession all your life, be desperate for a cure and spent thousands of hours reading about drugs, nbci papers and anecdotal experiences
>>
>>8913475
>Buy meds from online Indian pharmacies
Specifically interested in this part.
I only know about ab.
>>
>>8913478


The only legit online pharmacy I know of, is AllDayChemist. I am sure there must be others, but you'll have to do research on your own to find them. Shouldn't be hard with Reddit around.
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>>8913432
Man I've taken idra-21 a bunch of times now and haven't noticed any effects at all

What dosage/roa do you use?
>>
>>8913487
It's been a long time since I was experimenting with that stuff but I think I was taking either 5-10 or 10-20 mg either oral or sublingual. I can't remember. The main thing drugs of that category (pramiracetam has some function similar idra-21 that most racetams don't, again it's been a while since I was into this stuff so my apologies for forgetting the specifics like the name of that class of drugs) do to me is improve my auditory memory. I constantly had music stuck in my head when I normally can't visualize sound very well. Idra-21 had odd emotional effects on top of that. Plus the half life is so damn long that one dose is a 3 day commitment.

The emotional effects are hard to explain. There is a post somewhere on the Internet that you'll come across if you're researching idra-21 where somebody talks about obsessing over suicide after taking it. I can kind of understand that, it put me in kind of a dark place but I've been obsessed with suicide for a while. Something like a bad mood isn't going to make me fantasize more. It had me somewhat spacey but in a darker place than usual, while not being aware of my own mental state as much. I don't like it. I like listening to Vivaldi's winter on repeat in my head but I don't like the strange dark feeling. Most people seem to report not feeling anything from it though.
>>
>all this reddit

G T F O
T
F
O
>>
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>>8913521
>>
>>8913516

>I constantly had music stuck in my head when I normally can't visualize sound very well


Statements like these make me question the differences in people with it comes to distinct types of mental ''capacities'' or habits. I have always had music stuck in my head, I don't think it ever really stops.
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>>8912829
A moderate dose of addy will turn any brainlet into a mini Einstein for a few hours

Go for it, OP
>>
>>8913612
I love music but it's one of those things that I'll never have the intrinsic ability necessary to be successful with. Some of the nootropics I experimented with were wonderful just to be able to hear music with such clarity. But I don't need it for what I do now and some of the side effects weren't worth it.

I've generally viewed intelligence as broken up in to a lot of different areas. I clearly have a good visual memory and terrible auditory memory. I'm good at problem solving and creativity but I have a hard time remembering certain types of information (I can't remember dates and names). But with memory stuff, it's all about finding memory techniques that work with your mental skill set and timing review for adding to longterm memory. Stuff like chunking and reviewing after the proper duration has passed.

I apologize for typos or poor structure. I've had a few drinks so structuring my writing properly is hard, writing itself is quite fluid.
>>
>>8913645
Not entirely true, they'll feel like a mini Einstein. They're not much smarter than usual, but goddam it will they try.

It's something like alcohol myopia with amphetamines. You think you're quite smart but you're maybe just slightly better and more focused. And you can talk with high density and more confidence than you ought to have.
>>
Hello my fellow smart people I need your help I need you to teach me about the global climate change warming stuff you know what I mean like the ice sheets and shit I'm not the brightest person and I want to learn about that so I can become A legislature and legislate law that allows me to torture those who deny climate warming like Bill Nye you know what I mean thanks in advance my science Bros up-top what the hell was that? You're fucking high dude
>>
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I had one of my best drug experiences the first time I tried 20mg of Dexamphetamine. I went for a walk in the park at 3 am, every thing from lamps to the flowers looked beautiful and complex, I had a constant rush of songs, ideas and concept artwork in my head that was just incredible. I felt invincible, but the thing I liked most about it was just being able to get lost in my own mental images, seeing majestical worlds in the dark.


It's was such a contrasting experience compared to my usual dysthymic self, I cannot imagine how much productive and happy I would be if everyday was just half as good as that one. It made me consider seriously whether or not it is worth it to just jump into doing a low dose of meth more frequently for productivity and creativity purposes, I am so tired of procrastination.
>>
>>8913647

5 years ago I used to have a pretty decent auditory memory and imagination. I remember mixing songs together in my head, trying to come up with new things that I felt went really well together, I remember getting goose bumps just doing that sort of stuff.


But, after going through depression and a concussion that left me with tinnitus for life, all of that went away. I still have songs in my head, but they are more of a torture OCD thought that never stops, I wonder if there's any Nootropic out there that might help me get back some of my lost abilities. Might give Idra-21 a try.
>>
>>8913759
I'd go for pramiracetam instead. It's a similar class of drug and I've never heard report of emotional disturbances. I also use to get songs stuck in my head after taking it.
>>
>>8913774

>pramiracetam

Is it any different than Aniracetam? Already tried that one, gave me euphoria the first and second time I used it but afterwards, completely nothing despite using a choline source.
>>
>>8913788
There are distinct differences between the various racetams. Pramiracetam is somewhat unique compared to the others. I have some aniracetam but that was the only one I never tried. Piracetam made me somewhat manic temporarily. After a week I was just tired though. It's possible that was caused by other factors or a combination of things though. Coluracetam and noopept were noticable but didn't seem to offer any significant benefits. Oxiracetam didn't do anything noticable.

Pramiracetam is also an ampakine like idra-21 whereas most racetams either aren't or are very weak.

I also noticed it was much easier to concentrate after large quantities of caffeine when I took phenylpiracetam.

Honestly, most of the racetams don't have significant effects in my experience. Except pramiracetam just for the ampakine properties.

Also, it's been years since I even thought about this stuff so my information could be slightly off.
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>>8915054

I just bought a 6 month supply of Selegiline and some Levodopa/Carbidopa. I'll will be giving it a try to see what effects it has on cognition & drive. My main interest is becoming a productivity freak.

-
NCBI reports seem fairly decent, despite the drugs unpopularity compared to Adderall. Might try to do an Erowid report on it.
>>
>>8912901
take a racetam
>>
>>8915963
Never heard of levodopa and carbidopa. I'll have to look into it.

Just make sure you know what you can and cannot eat as well as what medications are safe with the selegiline. Mao inhibitors are a hassle.

I was looking for the same thing as you but I never had any luck with all the stuff I tried. Adderall was the best for me personally but one really ought not take amphetamines for a while. They're terrible for your brain.

Good luck with your new drugs though. Hope they work out for you.
>>
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>>8916040

The info is very interesting, specially the talk about Selegiline +L Dopa and Cabergoline combo causing an increase in creative, artistic drive in Parkinson patients. I suspect it must be due to increase D2 receptor activity?

>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804584/ (Combo)

And, here's a report (of many) of the effectiveness of Selegiline in treatment resistant depression.

>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804584/
It all looks very promising, and considering Dexamphetamine has always worked well for me I suspect Selegiline might just be what I am looking for (I stopped taking it for the same reasons as you, I don't want to destroy my brain with long term Amph usage). Gonna try to keep the positive emotion down though, to keep the placebo at bay.


Good luck to you too, pal.
>>
>>8915990

No more money left for drugs now, next drug in line will be PRL-8-53 and perharps, Galantamine or Huperzine A for experimenting with Lucid dreaming. Might consider Racetams in the future, Pramiceratam probably.
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