Ketone Bodies

>>8811136
Because God did it and he is proven to be a retarded engineer.

>>8811136
Insulin is needed to promote glycolysis. In its absence, gluconeogenesis takes place.

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>>8811179

File: Screen Shot 2017-04-07 at 2.18.16 PM.png (267KB, 1028x622px) Image search: [Google]

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no insulin (at least in type 1 DM, problem with type 2 is they produce insulin but either the receptor or signaling cascade is fucked up...hence why type 1 diabetics are skinny and type 2 are fatasses)

File: Screen Shot 2017-04-07 at 2.20.52 PM.png (155KB, 570x762px) Image search: [Google]

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you can see where PFK and FBPase fit in to the whole pathway

There's no insulin available, so the glucose is stuck in the blood. It needs to be in cells for gluconeogenesis.

DKA basically doesn't happen in type 2 diabetes

>>8811206
type 2 is not always fatasses, they dont utilize the sugar in their blood for energy

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>>8811255
>,
okay not "alway", but until their beta cells burn out they're pumping out fuck tons of insulin....which activates fatty acid uptake and triacylglycerol storage in adipose tissue, and triacylglycerol synthesis pathways. There is a reason that the majority of DM II people are fat fucks.

Thank you, anons. I think I got the whole picture now. :)

And don't matter the energetic level of the cells (Low atp or high ATP) the hormonal response is always going to be stronger?

>>8811136

>>8811236
This. Blood glucose =/= biologically available glucose, especially so in a diabetic.