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Psychedelic substances restoring Neuroplasticity

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Evidence has shown that ingesting psychedelic substances can restore a degree of neuro-plasticity to the brain. I'm not sure if many of you would be familiar with the concept of 'perfect pitch.' Perfect pitch is a coveted skill within the musical community that is simply the ability to recognise a note without a reference tone. This makes musical analysis and transcription incredibly easy, and revolutionises your coherency of musical theory. However, the skill can only be acquired when you are very young, when your brain is still learning and is flexible.

If I were to ingest a psychedelic substance and literally sit at my piano and play a single note for the entire duration of the trip, would I afterwards have created some neurological connection with that note that would persist even when the substance is out of my body?

I've been thinking about this for a while, some external feedback would be greatly appreciated.
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>>8732915
While some may increase growth factors like BDNF, neurogenesis still occurs in adulthood, at least in the subventricular zone. There's no proof that these neurons survive and differentiate elsewhere in the brain.

SSRI's, fasting, and exercise all increase growth factors too. On their own, while growth factors may encourage new synapse formation.

Overall I'm not convinced your experiment will work, but it can't hurt to try.

t. neuroscience grad student who doesn't care for music or serotonergic hallucinogens (I'm assuming you're not referring to ketamine and similar NMDA antagonists with the umbrella term "psychedelic")

Anecdotally, when I was younger I had many friends who liked to play music and stuff while tripping and while some of them were quite serious in their pursuit of music, none of them had perfect pitch.
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as someone who does psychs and plays piano..

no, just play like you normally do
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>>8732985
Whoops that was written poorly but I'm too tired to care. Effectively what I meant to communicate is that increasing neural growth factors doesn't necessarily increase learning. And I'm not sure if exposure to the same note again and again helps. Since I pretty much never read any papers involving auditory stuff.

Also I should say this is out of my area of research.
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>>8732988
Why is Yuja Wang so hot?
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>>8732988
She makes me wang hard.
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>>8732915
You can learn perfect pitch as an adult too, it's just harder.
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