How do we stop cardiovascular diseases?

>>8458742
killing people with cardiovascular diseases
t. darwinist

Exercise, don't eat lots of crappy food and don't smoke

>>8458774
This. And if you happen to be genetically unlucky then do your best at the above and prepare your thorax for a bypass surgery and a shitload of pain and inconvenience.

>>8458774
Too bad genetics ruins everything

>>8458763
A collective suicide would be better

>>8458742
Veganism.

>>8458790
>>8458793
There's no gene that makes it impossible to lose weight

>>8459004
High blood pressure and cardiac problems often run in a family.

>>8459011
nobody runs in your family

>>8459029
*ba dum tsss*

>>8458742
We could stop diseases if medfags were good at their jobs.

>>8458914
homocysteinemia is not friendly to the cardiovascular system

>>8459281
So take a supplement. It's better for you than eating an animal that has taken the supplement. Modern cattle only provides B12 because it's given B12.

>>8459029
kek

>>8459242
>he doesn't exercise
>fat af
>lazy af
>smokes
>drinks
>eats a lot of high caloric food cuz "muh delicious"
>comes up to a medfag
>OH HEY DOC CAN U REMOVE MY FATASS SO I CAN SEE MY DICK?

>>8459346
this desu

>>8458742
Jesus will heal all your ailments if you accept him in your heart.

>>8459029
Kekked! No but there is a hereditary factor associated with atherosclerosis.

>>8458742
go run outside, problem solved my nigga

>>8459318
B12 isn't the only factor. You also have the low overall low protein / DIAAS, sulfur-containing amino acid, and taurine content of the diet, and depletion via O-methylation and glycine conjugation reactions involved in phytochemical detoxification which choke the transsulfuration pathway.

>It's better for you than eating an animal that has taken the supplement
No, because then you miss out on health-promoting bioactives unique to animal source foods.

>Modern cattle only provides B12 because it's given B12.
Cattle synthesize B12 in their rumen from dietary cobalt. You're talking out of your ass or generalizing from some fringe practice on a few farms.

>>8458914
>Veganism.
That way we'll never live long enough to have to worry about heart disease?

>>8458742
>How do we stop cardiovascular diseases?
Eat more fish/shellfish.
Live less stressful lives.
Live less sedentary lives.

>>8459872
vegans demonstrably live longer lad

>>8458793
You're half right, in that viruses can influence genes some of the time as well.

>>8458774
That's health industry bullcrap. The real cause of these diseases is viral and bacterial infection and sometimes genetic history. Cytomegalovirus is the actual cause of heart disease, not lifestyle. Look it up.

>>8460069
Can you post some evidence for a robust relationship between CMV and cardiovascular risk?
I had a quick look and the consensus seems to be that there may be some very minor increased risk but no evidence to suggest CMV is the 'actual cause' of cardiovascular disease. For example a study in PLoS from 2011 couldn't show an effect on cardiovascular risk after adjustment for known confounders (ie smoking, obesity and diabetes). The scary sounding relative risk increases that they include in the conclusion are pretty meaningless without adjustment.

>>8460240
Here is the study - open access so the pdf is available. The conclusion is, in my opinion, pretty misleading.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0016103

It is a bacterial infection. Same one that rots teeth. I know. I have no teeth and I've had 100% blockages.

>>8459880
Than retards who don't give a shit about their health, diet, lifestyle, or sedentariness? kek

>>8460069
>viral and bacterial infection

Those might accelerate atheroma development, but they are not causal.

http://journals.lww.com/co-lipidology/Fulltext/2016/10000/The_central_role_of_arterial_retention_of.6.aspx

>>8460284
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673691/

The implication being that in this case, it's the factor that actually causes the illness, and without it cholesterol would barely cause a thing.

>>8460240
>Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection. S Li, J Zhu, W Zhang, Y Chen, K Zhang, LM Popescu, X Ma, WB Lau, R Rong, X Yu, B Wang, Y Li, C Xiao, M Zhang, S Wang, L Yu, AF Chen, X Yang, J Cai. Circulation 2011 Jul 12;124(2):175-184. "Using microarray-based miRNA expression profiling, we compared the miRNA expressions in plasma samples from 13 hypertensive patients and 5 healthy control subjects. Twenty-seven miRNAs were found to be differentially expressed. The expressions of selected miRNAs (miR-296-5p, let-7e, and a human cytomegalovirus [HCMV]-encoded miRNA, hcmv-miR-UL112) were validated independently in plasma samples from 24 hypertensive patients and 22 control subjects. The absolute expression levels of hcmv-miR-UL112, miR-296-5p, and let-7e were further determined in 127 patients and 67 control subjects (fold changes are 2.5, 0.5, and 1.7 respectively; all P<0.0001). Additionally, we demonstrated that interferon regulatory factor 1 is a direct target of hcmv-miR-UL112. Increased HCMV seropositivity and quantitative titers were found in the hypertension group compared with the control group (52.7% versus 30.9%, P=0.0005; 1870 versus 54 copies per 1 mL plasma, P<0.0001). Seropositivity, log-transformed copies of HCMV, and hcmv-miR-UL112 were independently associated with an increased risk of hypertension (odds ratio, 2.48; 95% confidence interval, 1.48 to 4.15; P=0.0005; odds ratio, 1.97; 95% confidence interval, 1.58 to 2.46; P<0.0001; and odds ratio, 2.55; 95% confidence interval, 1.98 to 3.27; P<0.0001, respectively)."

https://www.ncbi.nlm.nih.gov/m/pubmed/21690488/

3 Sep 17;2(8351):644-647. 132 patients

https://www.ncbi.nlm.nih.gov/pubmed/6136795

>>8460240
>Cytomegalovirus antigen within human arterial smooth muscle cells. JL Melnick, BL Petrie, GR Dreesman, J Burek, CH McCollum, ME DeBakey. Lancet 1983 Sep 17;2(8351):644-647. 132 patients with atherosclerosis after blood-vessel surgery. More than 25% of plaque and biopsy samples contained CMV antigens.
Melnick - Lancet 1983 abstract / PubMed
>Cytomegalovirus and atherosclerosis (letter). MS Smith, PC Venter, JL de Wet. S Afr Med J 1984 May 19;65(20):793. No abstract.

https://www.ncbi.nlm.nih.gov/m/pubmed/6136795/

>Herpesviridae in the endothelial and smooth muscle cells of the proximal aorta in arteriosclerotic patients. F Gyorkey, JL Melnick, GA Guinn, P Gyorkey, ME DeBakey. Exp Mol Pathol 1984 Jun;40(3):328-339. Electron microscopy of biopsies of 60 patients with atherosclerosis undergoing cardiovascular surgery. "Virions of the Herpesviridae family were observed in ten of the patients. They were detected in occasional smooth muscle and rare endothelial cells."

https://www.ncbi.nlm.nih.gov/m/pubmed/6723937/

There's more studies if you want them. Cytomegalovirus is also implicated in COPD.

Stop eating sugar

My Dad and all 4 of his brothers have had heart attacks after the age of 45. I've got a healthy BMI and regularly exercise but it feels bad eventually I can't do anything to stop it.

>>8460852
The case here is that this is not designed in a way that could be used to to support your claims. Wild type C57BL/6 mice are, unlike humans and most other primates, HDL animals and don't experience diet-induced elevations in atherogenic lipoproteins without another compounding factor. The inflammatory background stimulus from acute MCMV infection (with much bigger effect sizes on biomarkers than HCMV btw, which has a quite difference course) is probably acting to interfere with hepatic catabolism of said lipoproteins (they didn't measure plasma lipids) to drive what they're seeing. Human disease on the other hand takes decade to develop.

>>8458774
>don't smoke
That aint gonna happen anytime soon nigga