Pick one of three. What should I do?

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I don't know what to do with myself.

I'm firmly established in a group of friends. I'm the "weird as hell but sorta funny and earnest" one, supposedly. Also "the nice guy with the easy grin". Also "that fucking autist, but we like him". I like them a lot, but a good part of it is lies, simply because I hide so much.

I'm anti-homosexual. I like gay people just fine, but I don't like actual homosexuality. Several of my closest friends are bi or gay, but have no idea about this, as I've kept quiet.

I'm a Biblefag, but I can't even be assed to go to church.

I fucking suck at school. I'm going into my third year of college soon, and I failed Chemistry, which destroyed my dreams of becoming an endocrinologist to help other diabetics. I can't risk taking it again or else I'll lose my financial aid. I don't know what to study or what job to pursue.

I literally can't view a person who is trans as their "stated gender". I try to avoid using gendered pronouns altogether to avoid offending them, but I can't lie to myself about that. The few trans friends that I got don't know this, either.

I may or may not be find some men attractive myself. I'm consistent about my views on life, which means that I DO hold that against myself.

I don't give a shit about politics. My friends are pretty involved and care a lot, but the anger and hatred that politics tends to inspire in people stresses me the fuck out. People keep asking me why I'm so irresponsible.

I still get nervous around most cute girls (and some particularly handsome guys) like a kid, despite being in my early twenties. I have literally never dated before.

Do I come clean about my problems and let them judge me? Should I just off myself somewhere that nobody will find me? Do I keep quiet and keep going as if nothing's wrong? Somewhere in between? This pain is getting fucking unbearable.