If Italy ever aspires to be a superpower instead of a junior player or vassal state they need to focus on Mediterranean integration. Any European Latin Union will inevitably be dominated by France, any European union will be dominated by Germany. Iberia prevents Italy from getting a sphere of influence in the Americas.
If Italy can hold up their positions from Veneto to Genoa, I'd be surprised.
The old saying that Africa begins from the Alps might become reality.