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Heroin Vaccine has Successful Trials in Primates

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Thread replies: 29
Thread images: 4

File: heroin.png (160KB, 1190x556px) Image search: [Google]
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http://www.newsweek.com/new-vaccine-stop-heroin-high-abuse-study-622312

Here, the Scripps investigators, working with researchers at Virginia Commonwealth University, tested the vaccine on four rhesus monkeys. The animals were given three doses of the vaccine, which elicited a successful immune response that neutralized heroin given at varying doses. The high-blocking effects of the vaccine were strongest during the first month but continued for more than eight months. The researchers did not observe any harmful side effects from the intervention.

Two of the animals had been exposed to the vaccine seven months before for a similar pilot study. All four monkeys responded to the vaccine, but the two that were receiving it a second time had a stronger response, hinting that their immune systems were already primed with the “memory” of the compound.

Although research on humans is not yet planned, study authors Kim Janda and Paul Bremer, chemists at the Scripps Research Institute, are encouraged about this next step. Other anti-heroin vaccines have proved ineffective for people, but this compound is the first to work in primates. “We believe this vaccine candidate will prove safe for human trials,” said Janda in a statement.

Importantly, this vaccine is designed to work against only heroin, not other opioids. Bremer and Janda now hope to find a company interested in conducting a human study so that the vaccine can become commercially available.
>>
>>129558637
Archive shills https://archive.is/lBSos
>>
What is this "vaccine"? How could it not effect natural endorphin transmission in the body? This whole thing bothers me. There are no free rides when it comes to fucking with hormones and neurotransmitters.
>>
File: Heroin4.jpg (306KB, 1846x1306px) Image search: [Google]
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>>129558663
Um thanks!

http://archive.is/kgujp
>>
>give addict vaccine during rehab
>let them out
>they try to shoot up
>they try to shoot up 10 more times to get the same feeling as before
>they die quicker
>>
>>129558942
its a bot
>>
File: HeroinVaccine.jpg (296KB, 2336x780px) Image search: [Google]
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>>129558905
http://sci-hub.bz/10.1021/jacs.7b03334

Immunization of mice with an optimized heroin-tetanus toxoid (TT) conjugate formulated with adjuvants alum and CpG oligodeoxynucleotide (ODN) generated heroin ‘immunoantagonism’, reducing heroin potency by >15-fold.

Simplified schematic of heroin conjugate immunological pathway and mechanism of action. Upon vaccination, the
conjugate is taken up by dendritic cells (DCs), processed and displayed on the major histocompatibility complex class II (MHCII) as a haptenated peptide for activation of helper T-cells (Th-cells) via the T-cell receptor (TCR). B-cells which have encountered the conjugate via their B-cell receptors (BCR) are stimulated by activated Th-cells.

Adjuvants alum and CpG ODN enhance the vaccineresponse through NLRP3 inflammasome and TLR9 signaling, respectively. Memory B-cells and plasma cells produce high affinity anti-6AM IgG antibodies which bind to an administered heroin dose (converted to 6AM) in the periphery, thus mitigating drug effects in the brain.
>>
>>129559122
I know
>>
>>129558637
bump
>>
heroin-tetanus toxoid? generating immmunoantagonism??? Are these effects irreversable? Who knows how this impacts the natural processing of hormones and neurotransmitters? Fuck NO on this!
>>
>>129558637
bump
>>
>>129558637
bump
>>
>>129558637
bump
>>
>>129559560
this
spending the rest of your days without natural opioids suffering from the slightest bruise or cuts
>>
>>129561458
They reverse after a few months.
>>
>identify problem
>solve symptom
>ignore cause
>profit
>>
>>129558637
bump
>>
>>129558637
bump
>>
>>129558637
Taking away cravings from caged chimps is one thing - stopping a person who has lived, breathed and consumed nothing but heroin culture for the peroid of their addction - people who only have other addicts as friends - stopping these individuals from going back on heroin is impossible. Offer them the moon on a stick, they will come back to heroin.
You cannot cure heroin addiction. Even if they become 100% clean they always go back on it. I have worked with addicts, and known many in RL, they majority of whom are either dead or dying.
Best remedy? The Chinsese cure. Nobody goes back on heroin with a single dose of lead-based heroin subsitutes to the back of the cranium..
>>
>>129563761
I know people who quit it. They do other drugs still, but not heroin.
>>
>>129561588

this.

might as well pave the way for absolute degeneracy
>>
>>129558942
Oh shit, I guess you're putting Afghanistan to good use
>>
>>129564996
Very little of the heroin we use here is from there though.
>>
>>129565026
Go back to your churches America even in heresy God protected you till now.
You abandoned him to twerk instead and he's abandoning you.
>>
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>>129561531
I could still see it causing something horrendous like autoimmune disease against your own opioids in rare cases.

>>129563761
>>129561588
Yep, this is clearly a case where prevention is WAY better than cure. The US crisis was entirely caused by the Pharmaceutical Jew, who used heavy lobbying and paid shills to push known dangerously addictive opiates like OxyContin into much wider and longer term use. This vaccine is an attempt to extract additional shekels from the misery they've caused.

https://www.dailystormer.com/profit-from-pain-whos-behind-americas-opiate-epidemic/
>>
>>129565026
It's a fungible good, greater supply on the global market in general tends to lower the price and increase availability in any one location.
>>
>staying a junkie
>contracting autism

tough choice, burgers
>>
>>129560092
>>129560262
>>129560771
>>129562619
>>129563355
seems legit
>>
>>129564418
Given the option, they will go back on the smack, it's only matter of time and opportunity. Wait and see.
Thread posts: 29
Thread images: 4


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