I was wondering if you people could give me some suggestions

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I was wondering if you people could give me some suggestions of manga that deal with this theme:

>Personal growth (development) through effort and practice.

Some of my favorites in this line are Vagabond, Ikkyu, Buddha and Kokou no Hito.

I also like manga that are clearly made for adults and whose creators are greatly ambitious in an artistic, intellectual and even spiritual level, so I would also appreciate some suggestions on this line. I made a short list of titles that I think that fit in this pattern:

>Ayako
>Buddha
>The Book of Human Insects
>Phoenix
>Kokou no Hito
>Vagabond
>Real
>Barefoot Gen
>Berserk
>Nausicaä of the Valley of the Wind
>Akira
>Hajime no Ippo
>Ikkyu (unfortanelty I only found volumes 1 and 2 online; there are still volumes 2 and 3 left for me to read but I could find it for the life of me)

I would greatly appreciate suggestions.

*(tried this on /a/ already, but without success, so I am posting it now on the board on which I originally wanted to post – the quality of the minds and the emotional aspects of the psyche of the users is much better here)