I wonder if using a larger sector cluster size would shorten the lifespan of flash drives since now the reading/writing is done in 64k chunks.
>>62134678
Depends. The reason to do this, if you only write big files onto it(few extra kb/mb from index file). And if you read/write big files 64kb at the EOF doesn't matter much.
>>62135151
Yeah, I assume for small files the wear would be more significant. Programs in general, such as Firefox, VLC, etc.. which have many small file.
Don't worry your head about flash cycles, your drive won't end up RO anytime soon