Has any show ever referenced a meme?

Lots of times.

https://www.youtube.com/watch?v=ndA69KiffJE

https://www.youtube.com/watch?v=x8wOE7J8G1U

https://www.youtube.com/watch?v=3DH2oRZmZdc

>>84924829
Depending on your definition of meme, cartoons have been referencing memes for a very VERY long time. Just look at all the MAMMY jokes in early 30s cartoons.

>>84925062
https://www.youtube.com/watch?v=tmGU5yMf4eo

Family Guy has done stuff like Peanutbutter Jelly Time and Trololo

New Powerpuff Girls does

>>84925233
>>84925062
>real human meme
>and a real hero

>>84924829
>2016
>memes not everywhere

File: nome.jpg (77KB, 1280x720px) Image search: [Google]

77KB, 1280x720px

no anon. memes are obscure inside jokes of the internet, only really zany people like us even get the joke!

>>84924849
I miss MAD
https://www.youtube.com/watch?v=bTR9lSkPu4E

>>84924849
That had no right to be as good as it did.
I mean the humor on the mad show was always good but if it was going to fall down anywhere this would be it