Please help me help my friend

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Hey /adv/, I am in desperate need of some way to tell my friend he needs to get away from his family, and I just cant seem to bring myself to do it in fear of ruining our friendship.
>my friends 20, im 19
>we've been friends since 2nd grade
>he went to uni away from our home town, but still in state
>his dad died when he was 14
>he has basically raised his other two siblings and is pretty much the only father his younger half-sister has ever known
>his mother is horrifyingly codependant of him
>his mother basically followed him to college and never let him grow up
>it got so bad that he dropped out after his first year and moved back home
>he's working full time for the highschool that we both graduated from, just to turn around and give his paycheck back to his mother
>none of the rest of the family even attempts to care for themselves/their house
>their living in complete squalor while he runs around behind them trying to keep up (his sister has FAS syndrome and is incontinent)
I've basically watched my best friend slowly dying while his family has leeched the life out of him. My issue with bringing it up to him is that he's so convinced that they couldn't live without him that he's completely stopped any and all of his social life just to take care of his mother and his siblings. I've brought up going back to college to him, but he avoids the conversation. I leave tomorrow back to college ( the one he went to for a year) and I want to try to talk to him about it before I leave. Any advice on how to approach this is appreciated.