my frand need halp

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so, my friend here is in a very unhappy relationship (been about 2 years) and, he doesn't get off to sex, he's not attracted to her, and its just annoying to talk to her and socialize with her.

But he is very afraid to break up with her, because she's ballsoffthewallls crazy, and she's literally been in psyche ward recently. He is 100% convinced (or knows) that she'll kill herself if they break up, and doesn't really want to deal with having a death on his hands.

He's kinda in a dark place, drinking everynight and stuff, and i think he really needs to be with someone who he can love and who loves him and makes him happy. I've met her, she comes over with him all the time (im renting a room to him), and she is pretty god damn boring, and not very attractive honestly.

What should he do? He's young (just turned 21), and wants to explore his life and have fun a little while why young.

What do? How does he let her down without having blood on her hands?