Would The Foundation universe, from the Isaac Asimov books, make

>>50729625
Honestly I would rather play in a game heavily inspired by foundation than a direct tabletop game. I think the early stories would be fun, uniting the star systems with superior technology and SCIENCE.

>>50729783
I haven't read Foundation (though it's on my list), but that sounds like a more imperialistic Star Trek.
Boldly assimilating where no man has assimilated before

>>50729957
It's literally the rise and fall of the roman empire in a sci fi setting.

>>50729957
You should definitely read the first three, as they are excellent.

The others, not so much.

I don't think they're really granular enough to work as tabletop games outside maybe Microscope, since the scope of the series is a thousand year stretch of time where entire generations kind of just have to get by as human civilization collapses and is generally bound to their own planets or subsumed by the Foundation for their own benefit.

Also the Mule was there at some point, but he was pretty quickly dealt with. And if any PCs try to influence the setting too much, they'd be dealt with in the same way through a means they have no defense against.

>>50730203
You could say the same thing about the Bible

Doesn't mean it wouldn't make a great setting, even without the millennium-spanning JUST AS PLANNED.