>make molecule hydrophilic >molecule can't pass blood-brain-barrier

I'm actually so retarded I deserve to be shot for making this thread. Please don't point out how dumb I am.

Dummy

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13KB, 190x254px

>>9083298

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>>9083298

>>9083298
>>make sure it fits into the active center of 5-alpha-reductase
Making something that only fits in that active center and isn't horribly toxic is a difficult problem.

>> make molecule hydrophillic
That may interfere with binding to the active site

>>9083357
I read your post...?

>>9083624
Conversion of testosterone to DHT occurs in the hair follicles themselves. Even if DHT is secreted and it finds its way to the hair follicles inhibiting the enzyme will do nothing to reset circulating levels of the hormone. Also what I proposed in OP which is useless is extremely difficult due to >>9083556.

Basically I proposed nonsense.

there are already plenty of 5 alpha reductase inhibitors known