Thread replies: 9
Thread images: 2
Thread images: 2
File: Hypothalamus.png (97KB, 692x526px) Image search:
[Google]
97KB, 692x526px
Genetic Factors as a Cause of Obesity.
Obesity definitely runs in families. However, it has been difficult to determine the precise role of genetics in contributing to obesity because family members generally share many of
the same eating habits and physical activity patterns. Current evidence suggests that 20 to 25 percent of cases of obesity may be caused by genetic factors. Genes can contribute to obesity by causing abnormalities
of (1) one or more of the pathways that regulate the feeding centers and (2) energy expenditure and fat storage.
Three of the monogenic (single-gene) causes of obesity are:
(1) mutations of MCR-4, the most common monogenic form of obesity discovered thus far; (2) congenital leptin deficiency caused by mutations of the leptin gene, which
are very rare; and (3) mutations of the leptin receptor, which are also very rare. All these monogenic forms of obesity account for only a very small percentage of obesity. It is
likely that many gene variations interact with environmental factors to influence the amount and distribution of body fat.
Thoughts?
Source:
Hall, John E. 2016. Guyton and Hall Textbook of Medical Physiology. 13th ed.
>>
>>39554680
>not a single mention to insulin resistance
Opinion discarded
>>
>>39554680
>Guyton
Guyton's god tier son
>20%-25% of cases
that doesn't sound too much
>>
>>39554735
Seeing as /fit/ only ever mentions hypothyroidism, which has a prevalence of ~4.5%, 20-25% seems like an awful lot to me.
>>
>>39554680
>Obesity definitely runs in families.
Nothing runs in obese families.
But seriously, fat parents feed their fat kids fattening foods. That's the "genetics" of 99% of obesity cases.
>>
File: 1461203611276.gif (3MB, 320x240px) Image search:
[Google]
3MB, 320x240px
>>39554680
>difficult to determine
>may be
>could be
>likely
this shit wouldn't pass for a wikipedia article
>>
>>39554771
>>39554791
epigenetics
And, it's gonna get a lot worse.
To be honest familiar, I'm pretty stoked about it
More fatasses= more pussy for us
>>
>>39554791
That is another factor yes:
The rate of formation of new fat cells is especially rapid in the first few years of life, and the greater the rate of fat storage, the greater the number of fat cells. The number of
fat cells in obese children is often as much as three times that in normal children. Therefore, it has been suggested that overnutrition of children—especially in infancy and, to a lesser extent, during the later years of childhood—can
lead to a lifetime of obesity. [Fat cells - adipocytes - are thought not to degenerate]
Source:
Hall, John E. 2016. Guyton and Hall Textbook of Medical Physiology. 13th ed.
>>
>>39554680
The reason obesity runs in families is because of shitty upbringing
Thread posts: 9
Thread images: 2
Thread images: 2